How breast cancer cells acquire drug resistance

Duke Cancer Institute researchers on a seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib have found a previously unknown molecular network that regulates cell death.

The discovery provides new avenues to overcome drug resistance, according to the researchers.

Key protein can offer fresh cure for depression: Study

The identification of a key protein responsible for reducing the number of new brain cells can offer a fresh avenue for treating depression, a new study has found.

Research at King’s College London has revealed how stress hormones reduce the number of new brain cells – a process considered to be linked to depression.

The researchers identified a key protein responsible for this process and successfully used a drug compound to block the effect, offering a potential new avenue for drug discovery and treatment.

Physical exercise could help women fight osteoporosis

Washington, May 7 (ANI): A physical exercise programme that is based on a very basic, rudimentary materials can significantly improve upper and lower limb strength as well as static and dynamic balance in women suffering from postmenopausal osteoporosis.

Montserrat Otero, a PhD holder in Physical Activity and Sports Sciences of the UPV/EHU-University of the Basque Country studied 68 women with postmenopausal osteoporosis of the age group 50 – 72, of whom 34 were randomly assigned to the Exercise Group and 34 to the Control Group.

Kids eating with parents ‘healthiest’

Children who eat the same meals as their parents are far more likely to have healthy diets than those who do not, a new study has revealed.

The study, which looked at 2,000 five-year-olds, suggested that eating the same food as mum and dad had a greater impact on a young child’s health than any other factor, including social background and snacking between meals, the Daily Express reported. (ANI)

Functional 3-D ‘heart patch’ created in lab

Making a breakthrough in cell-based therapies, Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue.

This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

The “heart patch” grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies – the patch conducts electricity at about the same speed as natural heart cells and it “squeezes” appropriately.

Skipping meals may make you buy more calories

Even short-term food deprivation not only increases overall grocery shopping, but leads shoppers to buy 31 percent more high calorie foods, a new Cornell study has revealed.

People skip meals for all sorts of reasons – dieting, fasting, insane schedules that make you forget to eat, said Aner Tal, PhD, from the Cornell Food and Brand Lab, lead author of the study.

“But it doesn`t matter why you skipped a meal, it can still make your nutritionist cry – making you buy more potato chips and ice-cream and less baby carrots and skim milk,” Tal added.

WHO removes India from polio endemic nations` list

The World Health Organisation (WHO) has removed India from the list of countries with active endemic wild poliovirus transmission.

In written reply to a question in the Rajya Sabha, Minister of State for Health and Family Welfare Abu Hasem Khan Choudhury said Polio free is certified for WHO regions by the Regional Certification Commission and not for individual country.

Breast milk can prevent intestinal problem in babies

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, a new study has revealed.

The story begins with a baby who is born too early, meaning before 36 weeks gestation, said senior author David Hackam, M.D., Ph.D., Watson Family Professor of Surgery, Pitt School of Medicine, and co-director of the Fetal Diagnosis and Treatment Center at Children`s Hospital.

Functional 3-D `heart patch` created in lab

Making a breakthrough in cell-based therapies, Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue.

This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines.

The “heart patch” grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies – the patch conducts electricity at about the same speed as natural heart cells and it “squeezes” appropriately.

5 `sudden symptoms` of stroke that could save lives

Washington, May 6 (ANI): Stroke is one of the leading causes of death and adult disability, but quickly recognizing the signs of it and seeking immediate medical care from specialists can minimize the effects of the disease or even save a life, say an expert at Cedars-Sinai Medical Center.

Stroke is no longer a disease only of the elderly. Nearly 20 percent of strokes occur in people younger than age 55, and over the past decade, the average age at stroke occurrence has dropped from 71 to 69.

Magnesium may be as important as calcium for kids` bone health

Washington, May 6 (ANI): Most parents make sure that their children drink milk and eat other calcium-rich foods, as it helps build strong bones.

Now, a new study has suggested that it would be beneficial if they also give their kids salmon, almonds and other foods high in magnesium — another nutrient that may play an important role in bone health.

“Lots of nutrients are key for children to have healthy bones. One of these appears to be magnesium,” said lead author Steven A. Abrams MD, FAAP, professor of pediatrics at Baylor College of Medicine in Houston.

Nutrition plays key role in oral health

There is a strong connection between the food people eat and their oral health, a recently updated position paper of the Academy of Nutrition and Dietetics has stated.

The Academy`s position paper highlighted that nutrition is an integral component of oral health.

The Academy supports integration of oral health with nutrition services, education and research. Collaboration between dietetics practitioners and oral health care professionals is recommended for oral health promotion and disease prevention and intervention.

Fish oil may not help prevent age-related blindness

Adding the carotenoids lutein and zeaxanthin, the omega-3 fatty acids DHA and EPA, or both to a formulation of antioxidant vitamins and minerals that has shown effectiveness in reducing risk of progression to advanced age-related macular degeneration (AMD) did not further help reduce the risk, a new study has found.

Age-related macular degeneration is the leading cause of blindness in the developed world, according to background information in the article.

Magnesium as important as calcium for kids` bone health: Study

Most parents make sure that their children drink milk and eat other calcium-rich foods, as it helps build strong bones.

Now, a new study has suggested that it would be beneficial if they also give their kids salmon, almonds and other foods high in magnesium – another nutrient that may play an important role in bone health.

“Lots of nutrients are key for children to have healthy bones. One of these appears to be magnesium,” said lead author Steven A. Abrams MD, FAAP, professor of pediatrics at Baylor College of Medicine in Houston.

Portable cancer diagnostic device adapted to detect TB

Massachusetts General Hospital (MGH) investigators have modified a handheld diagnostic device, which was first developed to diagnose cancer, to rapidly diagnose tuberculosis (TB) and other important infectious bacteria.

These portable devices combine microfluidic technology with nuclear magnetic resonance (NMR) to not only diagnose these important infections but also determine the presence of antibiotic-resistant bacterial strains.

Protesters demonstrate in Srinagar against supply of spurious drugs

Protesters staged demonstrations outside the state secretariat on Monday, against the supply of spurious drugs in government run hospitals, and demanded action against the culprits.

Langate Constituency legislator, Engineer Rashid said: “We are protesting against the drug scam, the genocide in Kashmir and the inefficiency of the state government. No action has been taken against the concerned ministers including Sham Lal Sharma and others. The officers are just blaming others.”

6 steps to prevent skin cancer

Washington, May 5 (ANI): In observance of May`s Melanoma and Skin Cancer Awareness Month, Seattle Cancer Care Alliance (SCCA) has provided tips for prevention and early detection.

When left untreated, melanoma is the most dangerous and aggressive form of skin cancer, accounting for more than 9,000 of the 12,000-plus skin cancer deaths each year.

Exercise may help prevent kidney stones in older women

New York, May 5 (ANI): Just a couple hours of exercise a week, of any intensity, can help prevent kidney stones from forming, a large study on women aged over 50 has found.

The study noted that even walking for a couple hours a week could cut the risk of developing this painful and common problem by about one-third, the New York Daily News reported.

Dr. Mathew Sorensen of the University of Washington School of Medicine in Seattle, who led the study, said that just getting a minimum amount of exercise could help.

Soon, injectable nano particles to control blood sugar in diabetics

Washington, May 4 (ANI): Researchers have developed a network of nano particles, which can be injected into the body, and release insulin when blood-sugar levels rise, maintaining normal levels for more than a week.

The research was conducted by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children’s Hospital Boston.

How type 2 diabetes develops

Researchers have developed a new mouse model, which answers the question of what actually happens in the body when type 2 diabetes develops and how the body responds to the medication.

Bilal Omar from Lund University in Sweden and one of the researchers behind the study said that the animal models for type 2 diabetes studies that earlier existed have not been optimal as they use young mice.

He said that their idea was to create a model, which resembled the situation in the development of type 2 diabetes in humans.

H7N9`s infection risks mapped

Scientists have mapped avian influenza (H7N9) risk based on the northwards migratory patterns of birds using environmental and meteorological data – from Zhejiang, Shanghai, and Jiangsu, to Liaoning, Jilin, and Heilongjiang.

The map comprises of bird migration patterns, and adding in estimations of poultry production and consumption, which are used to deduce future risk and to advice on ways to prevent infection.

Screen yourself from the sun, but beware of sunscreen myths

Doctors have time and again harped on the importance of using a sunscreen to protect one’s skin. For many, however, choosing the right sunscreen is a tough choice, what with scores of products with various SPFs (Sun Protection Factors) flooding store shelves.

Does higher SPF mean better protection? Not so much, say doctors, who warn against being misled by marketing gimmicks.

How grapes help reduce heart failure associated with hypertension

Washington, May 3 (ANI): In a new study, researchers have demonstrated that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes responsible for antioxidant defense in the heart tissue.

Grapes are a known natural source of antioxidants and other polyphenols, which researchers believe to be responsible for the beneficial effects observed with grape consumption.

Running at night latest fitness craze

Sydney, May 3 (ANI): Based on a new fitness trend sweeping the UK, the latest running craze is all about one thing – darkness.

And you don’t even have to get up at the crack of dawn for it. In fact, they’re at night and take place in pitch black with only a dimly lit head-torch to guide the way, the Sydney Morning Herald reported.

The names of these new events, dubbed “dark races”, range from cute (the “Moonlight Flit”), to cheeky (“Wild Night Run”) to frankly, a little scary (“Night Terror”).

7 simple lifestyle steps may decrease risk of blood clots

Washington, May 3 (ANI): Adopting seven simple lifestyle steps could help reduce your risk of these potentially deadly blood clots, according to a new study.

Every five minutes, someone in the United States dies of a blood clot in the legs (deep vein thrombosis) or lungs (pulmonary embolism), according to the American Heart Association.

In a large, long-term study, researchers followed 30,239 adults who were 45 years or older for 4.6 years. Researchers rated participants’ heart health using the seven health indicators from the American Heart Association Life’s Simple 7.