The American drone fired at least four missiles at a vehicle in the Barmal area of South Waziristan tribal region on Tuesday.
Pakistani officials said that the vehicle and nearby houses were destroyed in the “unauthorized” attack.
The United States has deployed its terror drones to launch airstrikes inside Pakistan’s tribal belt.
Relations between Islamabad and Washington have soured over the “unauthorized” attacks. Pakistan insists that the airstrikes by the unmanned aircraft violate its sovereignty.
Washington claims its drone strikes target militants, although casualty figures clearly indicate that the aerial bombings have led to the death of hundreds of Pakistani civilians.
—Agencies